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Guilty Gear Isuka is the tenth installment of the Guilty Gear series. While the gameplay remained almost the same as in previous titles, the game introduced a four-player battle mode and three new characters.

Characters

• GGI/Sol Badguy
• GGI/Ky Kiske
• GGI/May
• GGI/Chipp Zanuff
• GGI/Axl Low
• GGI/Potemkin
• GGI/Faust
• GGI/Millia Rage
• GGI/Eddie
• GGI/Baiken
• GGI/Testament
• GGI/Dizzy
• GGI/Anji Mito
• GGI/Johnny
• GGI/Venom
• GGI/Jam Kuradoberi
• GGI/I-No
• GGI/Zappa
• GGI/Bridget
• GGI/Slayer
• GGI/A.B.A
• GGI/Robo-Ky
• GGI/Robo-Ky II
• GGI/Leopaldon
• GGI/Zako-Dan

A.B.A, Robo-Ky MK. II, Leopaldon and the Zako-Dan make their debut to the cast of Guilty Gear.

A.B.A fights with her giant key-axe, Paracelsus. While her initial movement is slow and lacks an air dash, her second stance gives her faster movement and powerful attacks, at the cost of her own health.